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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
17.88
Human Site:
S616
Identified Species:
28.1
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S616
A
M
K
R
L
R
D
S
P
P
P
K
L
K
N
Chimpanzee
Pan troglodytes
XP_510301
627
67581
C568
G
N
W
Q
L
F
C
C
G
P
S
S
D
L
T
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S616
A
M
K
R
L
R
D
S
P
P
P
K
L
K
N
Dog
Lupus familis
XP_544614
968
105825
S903
A
M
K
R
L
R
D
S
P
P
P
R
L
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S617
A
M
K
R
L
R
D
S
A
P
P
K
L
K
N
Rat
Rattus norvegicus
Q62829
544
60692
P485
G
T
P
E
L
Q
N
P
E
R
L
S
A
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
V580
K
M
R
N
A
H
K
V
S
R
R
A
P
A
L
Chicken
Gallus gallus
XP_426393
667
74767
S602
A
M
K
R
L
R
D
S
P
P
P
K
L
K
N
Frog
Xenopus laevis
NP_001082100
650
73749
N589
A
M
K
M
I
R
D
N
L
P
P
K
L
K
N
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
E628
A
M
K
R
L
R
D
E
L
A
P
T
V
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
P580
R
I
R
D
M
Q
P
P
N
L
K
N
A
H
K
Honey Bee
Apis mellifera
XP_001122147
624
70155
K565
I
R
D
M
P
P
P
K
L
K
N
S
H
K
V
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
D513
K
P
D
F
P
G
R
D
S
M
T
L
L
F
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
N829
A
L
Y
L
I
A
T
N
G
T
P
K
L
K
E
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
N883
A
L
W
L
I
A
T
N
G
T
P
H
I
K
D
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
6.6
N.A.
6.6
100
73.3
60
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
20
N.A.
13.3
100
86.6
73.3
N.A.
26.6
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
7
14
0
0
7
7
0
7
14
7
0
% A
% Cys:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
0
47
7
0
0
0
0
7
0
7
% D
% Glu:
0
0
0
7
0
0
0
7
7
0
0
0
0
0
7
% E
% Phe:
0
0
0
7
0
7
0
0
0
0
0
0
0
7
7
% F
% Gly:
14
0
0
0
0
7
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
7
7
7
0
% H
% Ile:
7
7
0
0
20
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
14
0
47
0
0
0
7
7
0
7
7
40
0
60
14
% K
% Leu:
0
14
0
14
54
0
0
0
20
7
7
7
54
7
7
% L
% Met:
0
54
0
14
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
7
20
7
0
7
7
0
0
47
% N
% Pro:
0
7
7
0
14
7
14
14
27
47
60
0
7
0
0
% P
% Gln:
0
0
0
7
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
14
40
0
47
7
0
0
14
7
7
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
34
14
0
7
20
0
0
0
% S
% Thr:
0
7
0
0
0
0
14
0
0
14
7
7
0
0
7
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
7
7
7
% V
% Trp:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _